Top 10 worst diseases of humanity

Billions of years have passed since the appearance of the planet Earth to the present day. At first it was a bare piece of rock, but as a result of many different phenomena, the Earth acquired an atmosphere and life began to appear inside it! At the very beginning of its development, it was extremely primitive, but millions of years of evolution allowed the life that appeared a very long time ago to turn into us, people and into everything that you see around.

However, not all forms of life that once originated on the planet have acquired intelligence. Some of them have remained in the form of bacteria and microorganisms, which have undergone a number of changes over time. Some of these microorganisms are useful for humanity, for example, bifidobacteria, the presence of which in the body prevents the emergence of harmful microelements. However, such bacteria live in the vicinity of them, the appearance of which can cause an incurable disease, bringing unbearable torment to the carrier and even leading him to death.

Such microorganisms are so diverse that it is even surprising. Even more surprising is that they all have completely different effects on the human body, even if in a negative way. And although mankind knows a fairly large number of pathogens, the lion’s share of them is still unknown to us. Meanwhile, people affected by new diseases can appear at any moment and without proper treatment they are doomed.

Nevertheless, in the article below you can find out about ten of the most terrible diseases of humanity that have ever been known to people. Each disease is capable of causing unbearable torment and bringing a person to his deathbed.

10. Black pox

  • People infected: no information available.
  • Disease locations: the entire planet.
  • Source of occurrence: natural focus of the virus.
  • Causative agent: Variola major, Variola minor.
  • Treatment methods: etiotropic and pathogenetic therapy.

The mortality rate from this disease ranges from 20 to 90%. In the absence of timely vaccine administration, the risk of illness increases significantly. Smallpox itself is an extremely tenacious virus. It can be stored in ice or withstand temperatures up to 100 degrees Celsius without losing its destructive properties. Infected with smallpox begins to rot literally alive. In the event that a smallpox patient was able to survive, then as a result of the experienced disease, there are multiple scars on his body, and there is also a high probability of going blind.

9. Bubonic plague

Bubonic plague
  • People infected: no information available.
  • Disease locations: the entire planet.
  • Source of occurrence: natural focus of the virus.
  • Causative agent: Yersinia pestis 1
  • Treatment methods: antibiotics, sulfonamide.

During the outbreak of this disease in medieval Europe, more than half of the population parted with their lives. In total, the plague claimed the lives of at least 60 million people around the world. Alas, there is no more accurate number of the dead, because in those days there was no one to count the dead. This disease showed the complete helplessness of the medicine and religious cults of that time available at that time. The probability of dying from the plague was then 99%!

8. Spanish flu or Spanish flu

Spanish flu or Spanish flu
  • Infected people: 550 million
  • Disease locations: the entire planet.
  • Spawn source: unknown.
  • Causative agent: H1N1 virus.
  • Treatment methods: medicinal alcohol-containing drugs.

The Spanish flu is named after its place of origin, where a massive infection occurred in about half of the population of Spain. The disease was dangerous in that it had practically no symptoms and developed extremely rapidly. Some patients died from the Spanish woman the very next day after infection! According to the available records, of the half a billion cases of the Spanish flu, 70 million people have died from this disease. Among the dead was also a well-known sociologist from Germany, Max Weber.

7. Hutchinson-Guildford syndrome or Progeria

Hutchinson-Guildford or Progeria syndrome
  • People infected: 80 people.
  • Disease locations: the entire planet.
  • Spawn source: unknown.
  • Causative agent: Genetic defect
  • Treatment options: none.

Carriers of this disease are extremely rare; only about 80 cases have been officially confirmed. As a rule, the sick are doomed, since there is currently no way to combat this disease. The disease itself turns the body of a 10-12 year old child into a 90 year old man. The life of a patient with progeria is rather painful and very short, no more than 20 years. However, even among the carriers of this disease, there are exceptions. A prime example of this is Leon Botha, a famous South African blogger and DJ who was able to live to be 26 years old. And in 1986 in Japan, a case of a carrier of this disease was documented, who lived to almost 45 years.

6. Necrotizing fasciitis

Necrotizing fasciitis
  • Humans Infected: Unknown.
  • Disease locations: the entire planet.
  • Source of appearance: introduction of harmful microorganisms into an open wound after surgical intervention.
  • Causative agent: Stpetoocccua pyogenes
  • Treatment methods: amputation of the affected limb, intervention with surgery.

The disease necrotizing fasciitis is as rare as it has dire consequences. According to statistics, death occurs in 30-75% of cases. The only chance for the carrier of the disease to survive is to diagnose and amputate the infected limb in time. However, it is very difficult to diagnose this disease, since the first stage of the disease is marked only by fever. Although it is very difficult to become infected with necrotizing fasciitis, if there is no carrier of this disease nearby, it is rightfully included in the list of terrible diseases of mankind.

5. Lymphedema or Elemental Disease

Lymphedema or Elemental Disease
  • Infected people: 120 million
  • Locations of the disease: Africa, tropics.
  • Source of appearance: introduction of parasitic worms into the lymphatic vessels, frequent cases of frostbite, eczema of a chronic nature …
  • Causative agent: Brugia malayi
  • Treatment options: surgery, massage.

Although carriers of this disease may not fear premature death, in itself it is extremely unpleasant. Lymphedema can severely disfigure the human body, transforming some areas of the skin into shapeless flesh. More than 90% of cases of the appearance of this disease are registered in the tropics, since it is there that there are the necessary conditions for the emergence and development of special parasitic worms. It is extremely difficult to diagnose this disease, the focus of the disease itself looks like an almost imperceptible and completely not causing concern, soft tissue edema, which can then turn the limb into a terrible piece of flesh.

4. Tuberculosis

  • People infected: about a third of the world’s population.
  • Disease locations: the entire planet.
  • Source of occurrence: the introduction of tuberculosis bacteria into the lungs.
  • Causative agent: microbacterium tuberculosis (MBT)
  • Treatment options: anti-tuberculosis chemotherapy.

In the past, this infectious disease was incurable, so people affected by this disease died in 80% of cases. Most often, tuberculosis is found in the lungs of a person. The disease is most common among the lower strata of the population. Tuberculosis is currently treatable, but a full course of chemotherapy can take several months, and in rare cases, several years. However, if you start this disease, it can lead to serious consequences, up to and including death.

3. Diabetes mellitus

  • People infected: approximately 285 million
  • Disease locations: the entire planet.
  • Spawn source: unknown.
  • Causative agent: unknown.
  • Treatment options: blood sugar lowering medications, insulin therapy, strict diet.

This disease disrupts the work of insulin, the hormone that is responsible for the supply of glucose from the blood to the cells of the body. Diabetes mellitus is responsible for the development of many diseases that are extremely unpleasant for humans, and can even lead to death without proper treatment. The most famous diseases that develop due to diabetes mellitus include: heart attack, stroke, disruption of the eye vessels with subsequent blindness, and many others.


  • Infected people: 33-45 million
  • Disease locations: the whole planet
  • Spawn source: unknown.
  • Causative agent: Human Immunodeficiency Virus (HIV).
  • Treatment methods: none.

Despite the development of modern medicine, the disease is considered incurable. Those affected by this disease have almost no immunity. Even a common cold can lead to death. This disease is considered the final stage of HIV development. Moreover, you can get infected with this virus anytime and anywhere.

1. Cancer (oncology)

Cancer (oncology)
  • People infected: more than 14 million people every year
  • Disease locations: the whole planet
  • Source of occurrence: non-compliance with diet, excessive alcohol consumption, smoking, exposure to radiation and much more.
  • Causative agent: unknown.
  • Treatment options: surgery, radiation or chemical therapy.

This disease causes increased cell division. It causes the formation of tumors and edema in the human body. It is difficult to diagnose and often does not show any signs of being present in the body for a long time. A neglected oncological disease can cause a stop in the functioning of human organs, which becomes the cause of death.

Take care of your health! Carry out the prevention of treatment of these diseases in time so that you do not have to face their consequences!

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